Product Datasheet
CKAP4 Antibody
Catalog Number: 37490
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q07065
NCBI Gene ID: 10970
Gene Accssion: NP_006816
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human cytoskeleton-associated protein 4
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
- other_names:
- p63; CLIMP-63; ERGIC-63
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CKAP4 protein.
- Background:
- CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.?
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