Product Datasheet
CERKL Antibody
Catalog Number: 37485
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q49MI3
NCBI Gene ID: 375298
Gene Accssion: NP_001025482
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ceramide kinase-like
- appl_detail:
- Western blotting: 1:500-1:2000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CERKL protein.
- Background:
- This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD).?
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