Product Datasheet
AGAP2 Antibody
Catalog Number: 37484
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q99490
NCBI Gene ID: 116986
Gene Accssion: NP_001116244
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- PIKE; GGAP2; CENTG1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AGAP2 protein.
- Background:
- The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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