Product Datasheet
CENPE Antibody
Catalog Number: 37482
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q02224
NCBI Gene ID: 1062
Gene Accssion: NP_001804
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human centromere protein E, 312kDa
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- KIF10; CENP-E; PPP1R61
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CENPE protein.
- Background:
- Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.?
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