Product Datasheet  
SIGLEC6 Antibody  
Catalog Number: 37473  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O43699
    NCBI Gene ID: 946
    Gene Accssion: NP_001171018
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human sialic acid binding Ig-like lectin 6
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200
  • other_names:  
  • CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total SIGLEC6 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • The?SIGLEC6?gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.



 
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