Product Datasheet  
CD2AP Antibody  
Catalog Number: 37468  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9Y5K6
    NCBI Gene ID: 23607
    Gene Accssion: NP_036252
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human CD2-associated protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:100-1:300
  • other_names：  
  • CMS
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total CD2AP protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.



 
© Signalway Biotechnology All Rights Reserved.