Product Datasheet
CACNB2 Antibody
Catalog Number: 37456
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q08289
NCBI Gene ID: 783
Gene Accssion: NP_963890
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human calcium channel, voltage-dependent, beta 2 subunit
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- MYSB; CAVB2; CACNLB2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CACNB2 protein.
- Background:
- This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described.
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