Product Datasheet
GDF11 Antibody
Catalog Number: 37444
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O95390
NCBI Gene ID: 10220
Gene Accssion: NP_005802
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human growth differentiation factor 11
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- BMP11; BMP-11
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GDF11 protein.
- Background:
- The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
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