Product Datasheet
GINS1 Antibody
Catalog Number: 37395
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14691
NCBI Gene ID: 9837
Gene Accssion: NP_066545
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human GINS complex subunit 1 (Psf1 homolog)
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- PSF1; RP4-691N24.2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GINS1 protein.
- Background:
- DNA replication complex GINS protein PSF1?is a?protein?that in humans is encoded by the?GINS1?gene. The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. GINS1 is essential for function. Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro.
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