Product Datasheet
ELP3 Antibody
Catalog Number: 37392
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H9T3
NCBI Gene ID: 55140
Gene Accssion: NP_060561
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human elongator acetyltransferase complex subunit 3
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ELP3 protein.
- Background:
- ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity. Involved in cell migration.
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