Product Datasheet
PDE6C Antibody
Catalog Number: 37389
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51160
NCBI Gene ID: 5146
Gene Accssion: NP_006195
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human phosphodiesterase 6C, cGMP-specific, cone, alpha prime
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- COD4; ACHM5; PDEA2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PDE6C protein.
- Background:
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene. This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).
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