Product Datasheet
NEK9 Antibody
Catalog Number: 37380
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8TD19
NCBI Gene ID: 91754
Gene Accssion: NP_149107
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human NIMA-related kinase 9
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- Nek8; NERCC; NERCC1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NEK9 protein.
- Background:
- NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization.
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