Product Datasheet
PIP5K1C Antibody
Catalog Number: 37375
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60331
NCBI Gene ID: 23396
Gene Accssion: NP_001182662
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PIP5K1C protein.
- Background:
- This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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