Product Datasheet  
AURKC Antibody  
Catalog Number: 37365  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9UQB9
    NCBI Gene ID: 6795
    Gene Accssion: NP_001015878
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the N terminal of human aurora kinase C
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:15-1:50
  • other_names:  
  • AIE2; AIK3; ARK3; AurC; SPGF5; STK13; aurora-C
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total AURKC protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.



 
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