Product Datasheet
AURKC Antibody
Catalog Number: 37365
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UQB9
NCBI Gene ID: 6795
Gene Accssion: NP_001015878
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human aurora kinase C
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- AIE2; AIK3; ARK3; AurC; SPGF5; STK13; aurora-C
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AURKC protein.
- Background:
- This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
© Signalway Biotechnology All Rights Reserved.