Product Datasheet
RCAN2 Antibody
Catalog Number: 37363
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14206
NCBI Gene ID: 10231
Gene Accssion: NP_001238902
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human regulator of calcineurin 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CSP2; RCN2; MCIP2; ZAKI4; ZAKI-4; DSCR1L1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RCAN2 protein.
- Background:
- This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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