Product Datasheet
ARHGAP4 Antibody
Catalog Number: 37353
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P98171
NCBI Gene ID: 393
Gene Accssion: NP_001657
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human Rho GTPase activating protein 4
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- C1; RGC1; p115; SrGAP4; RhoGAP4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ARHGAP4 protein.
- Background:
- This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene.
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