Product Datasheet  
APBA2 Antibody  
Catalog Number: 37336  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q99767
    NCBI Gene ID: 321
    Gene Accssion: NP_001123886
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the N terminal of human amyloid beta (A4) precursor protein-binding, family A, member 2
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:100-1:300
  • other_names：  
  • X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total APBA2 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.?



 
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