Product Datasheet
SERPINF2 Antibody
Catalog Number: 37330
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P08697
NCBI Gene ID: 5345
Gene Accssion: NP_000925
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- AAP; API; PLI; A2AP; ALPHA-2-PI
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SERPINF2 protein.
- Background:
- This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
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