Product Datasheet
ALG11 Antibody
Catalog Number: 37327
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q2TAA5
NCBI Gene ID: 440138
Gene Accssion: NP_001004127/Q2TAA5
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ALG11, alpha-1,2-mannosyltransferase
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ALG11 protein.
- Background:
- This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP).?
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