Product Datasheet
AKT2 Antibody
Catalog Number: 37320
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P31751
NCBI Gene ID: 208
Gene Accssion: NP_001617
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human v-akt murine thymoma viral oncogene homolog 2
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AKT2 protein.
- Background:
- This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
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