Product Datasheet
ADAM12 Antibody
Catalog Number: 37309
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O43184
NCBI Gene ID: 8038
Gene Accssion: NP_003465
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ADAM metallopeptidase domain 12
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MCMP; MLTN; MLTNA; MCMPMltna
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ADAM12 protein.
- Background:
- This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
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