Product Datasheet
S1PR5 Antibody
Catalog Number: 37291
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H228
NCBI Gene ID: 53637
Gene Accssion: NP_110387
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Sphingosine-1-phosphate receptor 5
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total S1PR5 protein.
- Background:
- The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors are S1P receptors; others are LPA receptors.
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