Product Datasheet
TRPM7 Antibody
Catalog Number: 37281
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96QT4
NCBI Gene ID: 54822
Gene Accssion: NP_060142
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human transient receptor potential cation channel, subfamily M, member 7
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CHAK; CHAK1; ALSPDC; LTRPC7; TRP-PLIK
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRPM7 protein.
- Background:
- The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.
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