Product Datasheet
PTMA Antibody
Catalog Number: 37277
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P06454
NCBI Gene ID: 5757
Gene Accssion: NP_001092755
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human prothymosin, alpha
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PTMA protein.
- Background:
- Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections and as oncogenes contributing to cell proliferation and invasion in BC. Silencing of these gene significantly inhibited cell proliferation and invasion, and increased apoptosis in BC cells. Immunohistochemistry showed that PTMA expression levels were significantly higher in BC compared to normal bladder epitheliums.
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