Product Datasheet
SIGLEC7 Antibody
Catalog Number: 37470
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y286
NCBI Gene ID: 27036
Gene Accssion: NP_055200
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human sialic acid binding Ig-like lectin 7
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- p75; QA79; AIRM1; CD328; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SIGLEC7 protein.
- Background:
- Sialic acid-binding Ig-like lectin 7?is a?protein?that in humans is encoded by the?SIGLEC7?gene. SIGLEC7 has also been designated as?CD328?(cluster of differentiation?328). Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
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