Product Datasheet
PAFAH2 Antibody
Catalog Number: 37205
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q99487
NCBI Gene ID: 5051
Gene Accssion: NP_000428
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human platelet-activating factor acetylhydrolase 2, 40kDa
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAFAH2 protein.
- Background:
- This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.
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