Product Datasheet
SLC8A3 Antibody
Catalog Number: 37178
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P57103
NCBI Gene ID: 6547
Gene Accssion: NP_001123889
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 8 (sodium/calcium exchanger), member 3
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLC8A3 protein.
- Background:
- This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
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