Product Datasheet  
MYSM1 Antibody  
Catalog Number: 37175  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q5VVJ2
    NCBI Gene ID: 114803
    Gene Accssion: NP_001078956
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human Myb-like, SWIRM and MPN domains 1
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • 2ADUB; 2A-DUB; RP4-592A1.1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total MYSM1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.



 
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