Product Datasheet  
CDC25B Antibody  
Catalog Number: 37166  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P30305
    NCBI Gene ID: 994
    Gene Accssion: NP_004349
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human cell division cycle 25B
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • CDC25B; CDC25HU2; M-phase inducer phosphatase 2; MPIP2
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total CDC25B protein.
  • Applications：  
  • WB IHC
  • Background：  

  • CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.




 
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