Product Datasheet
TNFRSF17 Antibody
Catalog Number: 37151
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q02223
NCBI Gene ID: 608
Gene Accssion: NP_001183
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human tumor necrosis factor receptor superfamily, member 17
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- BCM; BCMA; CD269; TNFRSF13A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNFRSF17 protein.
- Background:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation
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