Product Datasheet  
BCL6 Antibody  
Catalog Number: 37150  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P41182
    NCBI Gene ID: 604
    Gene Accssion: NP_001697
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human B-cell CLL/lymphoma 6
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total BCL6 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene



 
© Signalway Biotechnology All Rights Reserved.