Product Datasheet
BAG6 Antibody
Catalog Number: 37146
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P46379
NCBI Gene ID: 7917
Gene Accssion: NP_004630
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human BCL2-associated athanogene 6
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- G3; BAT3; BAG-6; D6S52E
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BAG6 protein.
- Background:
- This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.?
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