Product Datasheet
ACPT Antibody
Catalog Number: 37143
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BZG2
NCBI Gene ID: 93650
Gene Accssion: NP_149059
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human acid phosphatase, testicular
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- acid phosphatase; testicular; ACPT; PPAT; Testicular acid phosphatase
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ACPT protein.
- Background:
- Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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