Product Datasheet
MAGEA3 Antibody
Catalog Number: 37138
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P43357
NCBI Gene ID: 4102
Gene Accssion: NP_005353/P43357
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human melanoma antigen family A, 3
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- HIP8; HYPD; CT1.3; MAGE3; MAGEA6
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAGEA3 protein.
- Background:
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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