Product Datasheet
SMURF1 Antibody
Catalog Number: 37123
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HCE7
NCBI Gene ID: 57154
Gene Accssion: NP_065162
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human SMAD specific E3 ubiquitin protein ligase 1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- hSMURF1; KIAA1625; SMUF1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SMURF1 protein.
- Background:
- This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.
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