Product Datasheet
GDF2 Antibody
Catalog Number: 37122
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UK05
NCBI Gene ID: 2658
Gene Accssion: NP_057288
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human growth differentiation factor 2
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- BMP9; HHT5; BMP-9
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GDF2 protein.
- Background:
- The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.
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