Product Datasheet
ITGA2 Antibody
Catalog Number: 37117
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17301
NCBI Gene ID: 3673
Gene Accssion: NP_002194
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ITGA2 protein.
- Background:
- This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
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