Product Datasheet  
ITGA2 Antibody  
Catalog Number: 37117  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P17301
    NCBI Gene ID: 3673
    Gene Accssion: NP_002194
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100
  • other_names:  
  • BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total ITGA2 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.



 
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