Product Datasheet
ARPC4 Antibody
Catalog Number: 37116
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P59998
NCBI Gene ID: 10093
Gene Accssion: NP_005709
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human actin related protein 2/3 complex, subunit 4, 20kDa
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- ARC20; P20-ARC
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ARPC4 protein.
- Background:
- This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.
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