Product Datasheet
AKAP1 Antibody
Catalog Number: 37094
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q92667
NCBI Gene ID: 8165
Gene Accssion: NP_001229831
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human A kinase (PRKA) anchor protein 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- AKAP; PRKA1; AKAP84; TDRD17; AKAP121; AKAP149; D-AKAP1; PPP1R43; SAKAP84
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AKAP1 protein.
- Background:
- The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
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