Product Datasheet
AGAP1 Antibody
Catalog Number: 37088
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UPQ3
NCBI Gene ID: 116987
Gene Accssion: NP_001032208
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- GGAP1; AGAP-1; CENTG2; cnt-g2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AGAP1 protein.
- Background:
- This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
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