Product Datasheet
AFF2 Antibody
Catalog Number: 37087
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51816
NCBI Gene ID: 2334
Gene Accssion: NP_001162593
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human AF4/FMR2 family, member 2
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- FMR2; MRX2; OX19; FMR2P; FRAXE
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AFF2 protein.
- Background:
- This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
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