Product Datasheet
BAZ1A Antibody
Catalog Number: 37079
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NRL2
NCBI Gene ID: 11177
Gene Accssion: NP_038476
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human bromodomain adjacent to zinc finger domain, 1A
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- ACF1; WALp1; hACF1; WCRF180
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BAZ1A protein.
- Background:
- Bromodomain adjacent to zinc finger domain protein 1A?is a?protein?that in humans is encoded by the?BAZ1A?gene. Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase.
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