Product Datasheet
FZD2 Antibody
Catalog Number: 37068
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14332
NCBI Gene ID: 2535
Gene Accssion: NP_001457
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Frizzled family receptor 2
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- Fz2; fz-2; fzE2; hFz2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FZD2 protein.
- Background:
- This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
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