Product Datasheet
TH Antibody
Catalog Number: 37059
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P07101
NCBI Gene ID: 7054
Gene Accssion: NP_000351
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human tyrosine hydroxylase
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- TYH; DYT14; DYT5b
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TH protein.
- Background:
- The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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