Product Datasheet
TRAF7 Antibody
Catalog Number: 37054
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6Q0C0
NCBI Gene ID: 84231
Gene Accssion: NP_115647.2
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human TNF receptor-associated factor 7, E3 ubiquitin protein ligase
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- RFWD1; RNF119
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRAF7 protein.
- Background:
- Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
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