Product Datasheet
VIMP Antibody
Catalog Number: 37045
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BQE4
NCBI Gene ID: 55829
Gene Accssion: NP_060915
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human VCP-interacting membrane protein
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- SELS; ADO15; SBBI8; SEPS1; AD-015
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total VIMP protein.
- Background:
- This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
© Signalway Biotechnology All Rights Reserved.