Product Datasheet
SYT2 Antibody
Catalog Number: 37044
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N9I0
NCBI Gene ID: 127833
Gene Accssion: NP_001129976
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human synaptotagmin II
- appl_detail:
- Western blotting: 1:500-1:2000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SYT2 protein.
- Background:
- Synaptotagmin-2 is a protein that in humans is encoded by the SYT2 gene. Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
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