Product Datasheet  
SRF Antibody  
Catalog Number: 37042  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P11831
    NCBI Gene ID: 6722
    Gene Accssion: NP_003122.1
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human serum response factor (c-fos serum response element-binding transcription factor)
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200
  • other_names:  
  • MCM1
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total SRF protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).



 
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