Product Datasheet
PAX2 Antibody
Catalog Number: 37014
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q02962
NCBI Gene ID: 5076
Gene Accssion: NP_000269
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human paired box 2
- appl_detail:
- Western blotting: 1:1000-1:3000
- other_names:
- paired box 2; Paired box protein Pax-2; PAX2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAX2 protein.
- Background:
- PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.?
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