Product Datasheet
PAX1 Antibody
Catalog Number: 37013
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P15863
NCBI Gene ID: 5075
Gene Accssion: NP_006183
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human Paired box 1
- appl_detail:
- Western blotting: 1:500-1:2000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAX1 protein.
- Background:
- This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations
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